Can Blighted Ovum Be Prevented? Here’s What You Can Do A blighted ovum happens mostly because of chromosomal problems during fertilization meaning the embryo was not developing normally from the start. Because of this, you cannot 100% prevent it, but you can reduce the risks and support healthier conception. Here’s what you can do: 1. Start taking folic acid before conception It helps support healthy cell division and reduces early developmental problems. 2. Check for chromosomal or genetic issu