What is perichondritis of the auricle and why should you care? Explained in 3D Perichondritis is a diffuse inflammation of the perichondrium, the thin layer of connective tissue that nourishes the cartilage of the auricle. Unlike other ear infections, this condition does not extend to the earlobe, as it lacks cartilage. If left untreated, perichondritis can lead to cartilage destruction and ear deformity, such as the characteristic "cauliflower ear" seen in untreated cases. In severe cases, necr