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🧬 What p53 does in minor DNA damage initially Cell-cycle arrest (pause, don’t kill) * p53 upregulates p21 * p21 inhibits CDK–cyclin complexes * 👉 G1/S checkpoint arrest * Purpose: give the cell time to repair DNA | Medical Addicts
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🧬 What p53 does in minor DNA damage initially Cell-cycle arrest (pause, don’t kill) * p53 upregulates p21 * p21 inhibits CDK–cyclin complexes * 👉 G1/S checkpoint arrest * Purpose: give the cell time to repair DNA | Medical Addicts
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