Human CD19 genome location and CD19 gene details page in the UCSC Genome Browser. This article incorporates text from the United States National Library of Medicine, which is in the …

CD19 is a biomarker for normal and neoplastic B cells, as well as follicular dendritic cells. CD19 is critically involved in establishing intrinsic B cell signaling thresholds through modulating both B …

Sep 17, 2025 · In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease …

May 14, 2021 · Defects in CD19 cause immunodeficiency common variable type 3 (OMIM #613493), characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial …

What is CD19? CD19 is a protein primarily expressed on the surface of B cells, a type of white blood cell that plays a key role in the immune system’s defense against infections.

Nov 13, 2025 · Complete information for CD19 gene (Protein Coding), CD19 Molecule, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human …

The CD19 antigen (aka B-lymphocyte antigen CD19 or Cluster of Differentiation 19) plays an important role in clinical oncology. It’s a protein found on the surface of B-cells, a type of white …

Apr 29, 2025 · CD19 is a transmembrane glycoprotein that modulates signaling thresholds during B cell maturation. Expressed from the early pro-B cell stage through mature B cells, it …

CD19 is a single-chain glycoprotein expressed on the surface of B lymphocytes and follicular dendritic cells, characterized by two immunoglobulin-like domains in its extracellular region.

Jan 7, 2026 · In the phase 1/2 CASTLE basket trial, autologous CD19 CAR-T cell therapy in patients with treatment-refractory systemic lupus erythematosus, systemic sclerosis or …