This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...

Spatial transcriptomics on human brains parsed microglial reactions to amyloid immunotherapy. Both a vaccine and a therapeutic antibody summoned these cells to plaques. Responders expressed TREM2, ...

Numerous studies have hinted that women are particularly susceptible to tau pathology, but scientists have lacked definitive data. Now, a meta-analysis of six longitudinal tau PET studies offers the ...

Erythropoietin-producing hepatocellular (Eph) receptors, including EphA4, are expressed on the cell surface and involved in brain development, which involves extensive pruning of synapses. A variant ...

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Sex Delta by Cell Type. In men with Alzheimer’s (top left), B cells (red boxes) were fewer (blue), while NK cells (blue boxes ...