Despite the defense's struggles, the San Francisco 49ers have publicly supported defensive coordinator Nick Sorensen ...

The San Francisco 49ers hit the road for the second consecutive week to face the Buffalo Bills on Sunday Night Football at ...

The San Francisco 49ers hit the road for the second consecutive week to face the Buffalo Bills on Sunday Night Football at ...

The San Francisco 49ers are facing an uphill battle in their quest to earn a playoff spot after suffering their second ...

The San Francisco 49ers face another tough test this weekend as they head to Highmark Stadium for a road matchup against the ...

The 49ers' season took a major downward spiral in the past two games. The loss to the Seattle Seahawks, which dropped the ...

Several reporters noted that San Francisco 49ers quarterback Brock Purdy was not on the field during the media-accessible ...

Deebo Samuel is not having a good season. When the 49ers throw him the ball, their quarterback rating is just 89.2. And when ...

The 49ers are getting linebacker Dre Greenlaw back at practice this week after he suffered an Achilles tear during the Super ...

The San Francisco 49ers plan to open linebacker Dre Greenlaw's practice window this week, paving the way for his highly ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters via a conference call on Monday, providing several injury ...

The San Francisco 49ers will hold three full practices this week as they prepare for their Week 13 matchup against the ...