Aged and frail people often suffer a decline in tissue reserve capacity during aging. This reserve, called resilience, helps ...

Researchers have discovered how sperm cells perform an extraordinary metabolic transformation after ejaculation, from quiet storage mode to full-speed motion in their mission to fertilize an egg. In a ...

Glucose metabolic reprogramming describes the alterations in intracellular metabolic pathways in response to variations in the body’s internal environment. This metabolic reprogramming has been the ...

Cancer cells are notorious for their ability to break the usual biological speed limits. They divide quickly, migrate toward blood vessels, and survive bouts of low oxygen that would stall most ...

The researchers say it was taught in biochemistry class for many decades that glycolysis occurred uniformly in the cytosol, or the fluid matrix of the cell. But when the Johns Hopkins team examined ...

Glycolytic waves drive and fuel cancer cell migration. The image, captured with a high-powered microscope over 9-minute intervals, is color-coded from early to late time points showing wave activity ...

This work presents valuable data demonstrating that a camelid single-domain antibody can selectively inhibit a key glycolytic enzyme in trypanosomes via an allosteric mechanism. The claim that this ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Alpha-enolase (ENO1) is a glycolytic enzyme that reacts with ...