Dive into the San Francisco 49ers vs. Buffalo Bills showdown with a look at odds, predictions, and the best betting options.

The Rams struggled to wrap up the Eagles last week. They are focused on delivering a sharper performance against the Saints ...

San Francisco 49ers vs Buffalo Bills showdown with essential stats, lineup predictions and injury updates you won’t want to ...

Green Bay's first of two 2022 first-round picks had arguably his two best games of the season the last two weeks.

Missed the last seven snaps of the loss to Packers and was placed on concussion protocol upon the 49ers’ return home, Banks ...

John Lynch shared positives from San Francisco's supbar 2024 NFL season with NBC Sports Bay Area's Matt Maiocco on "49ers ...

The team desperately need to win on Sunday to keep their hopes of reaching the postseason alive after what has been a testing ...

The Green Bay Packers and Detroit Lions are in much different shape physically following their grueling Sunday-Thursday gauntlet of games. The ...

San Francisco 49ers quarterback Brock Purdy is expected to return to the field on Sunday against the Buffalo Bills after ...

With the Miami Dolphins taking a 30-17 loss to the Green Bay Packers on Thursday night, the Buffalo Bills can wrap up the AFC East for a fifth straight season o ...

The NFL is just about as unpredictable as the Buffalo weather at this time of the year, so the 49ers will take their ...