Hypertension stimulates structural arterial remodelling, which is characterized by vascular smooth muscle cell (VSMC) hyperplasia and infiltration of inflammatory cells. The mechanisms of hypertensive ...
Global understanding of complement has shifted and developed since the 21st century: from our idea of a blood-based antibiotic system to a global regulator of immunity and tissue homeostasis. Recent ...
To provide insight into bacterial suppression of complement-mediated immunity, we present here structures of a bacterial complement inhibitory protein, both free and bound to its complement target.
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