In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

Granulation is a critical unit operation in pharmaceutical manufacturing, where fine powders are agglomerated into granules to improve flow properties, uniformity, and compaction performance. The ...

At the manufacturing level, pharmaceutical manufacturers are leveraging advanced technologies and automation to address challenges such as sample under fill and overfill, detect contaminants and other ...

We try to use previous experience to develop the optimal granulation process for each new ingredient, but we sometimes get it wrong. Many times, we?ve taken materials from the granulator only to find ...

Troy, Alabama-based KW Plastics is a large recycler of postconsumer high-density polyethylene (HDPE), polypropylene (PP) and other scrap materials. The company also produces products made of ...

Pharmaceutical manufacturing practices are advancing towards a future in which continuous manufacturing processes will be the norm. Developing and applying such techniques is therefore an essential ...

Although tablet manufacture is traditionally a batchbased wet granulation process, there are many advantages to be gained by adopting dry granulation, including lower costs and increased yields.

According to a recent poll of Pharmaceutical Technology readers (conducted by GlobalData)[i] 43% of respondents said that environmental issues were the most important ESG (Environmental, Social, and ...