Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 22 (May 29, 2018), pp. E5193-E5202 (10 pages) Store-operated Orai1 channels are activated through a ...
B lymphocytes have the ability to sense thousands of structurally different antigens and produce cognate antibodies against these molecules. For this they carry on their surface multiple copies of the ...
Effect of TT-816, a novel immune response modifier targeting cannabinoid CB2 receptor, on antitumor immunity and cancer growth. Antitumor mechanisms of OncoTherad (MRB-CFI-1) nanoimmunotherapy ...
A crucial step in preclinical drug development is the confirmation of the novel therapeutic molecule's specific binding to the targeted protein. Transmembrane proteins (TPs) like ion channels, ...
A study reported by researchers at NYU Langone Health’s Perlmutter Cancer Center and at the University of Oxford has offered up new insights into the workings of an immune cell surface receptor, ...
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