An invaluable source of RNA, DNA, and chromatin from historical and clinical samples is formalin fixed paraffin embedded (FFPE) tissue. Globally, tissue banks, hospitals, and laboratories are ...
The primary goal of fixation is to arrest the autolysis and putrefaction of tissues with the goal of stabilizing the morphological structure and biochemical relationships between constituent proteins ...
Formalin-fixed paraffin-embedded (FFPE) tissues are the most widely used clinical sample types in histology and molecular diagnosis. However, due to RNA degradation and protein crosslinking, FFPE ...
The following article is the first of a three-part series on imaging large whole mount brain sections for neuroscience research. The series covers sectioning/staining, scanning, and data management.