Two papers in tomorrow's Science provide long-awaited evidence for the notion that the two pathological hallmarks of Alzheimer's disease are interconnected. Using different approaches, teams led by ...

A team of researchers at Case Western Reserve University School of Medicine has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a ...

Despite its long and distinguished history in Alzheimer’s research, the microtubule-stabilizing protein tau still poses many a riddle to scientists. They do know that excessive phosphorylation of tau ...

Since the discovery of Alzheimer's disease over a century ago, two hallmarks of the devastating illness have taken center stage. The first, known as amyloid plaques, are dense accumulations of ...

SAN FRANCISCO, March 23, 2010 — A study of the brains of people who stayed mentally sharp into their 80s and beyond challenges the notion that brain changes linked to mental decline and Alzheimer's ...

Years before neurofibrillary tangles (NFTs) of tau protein show up in brain scans of patients with Alzheimer’s disease (AD), a biomarker test developed at the University of Pittsburgh School of ...

A team of researchers has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a hallmark of Alzheimer's disease and several other ...

In a new study, researchers investigate tangles in the brain -- pathologies not only characteristic of Alzheimer's but other neurodegenerative conditions as well. The research homes in on a particular ...