Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

Zimislecel is an allogeneic stem cell-derived islet cell therapy that could eliminate the need for insulin in those who have ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study led by ...

Acute myeloid leukemia (AML) cells under the microscope, in purple. There is a serious need for finding better ways to treat AML that comes back after initial treatment. Chimeric antigen receptor (CAR ...

Researchers at the Max Delbrück Center have found that a cellular housekeeping mechanism called autophagy plays a major role ...

Colorectal cancer breaks the usual immune rules, with certain regulatory T cells linked to improved survival. In many solid ...

Scientists have identified a promising strategy to improve liver cancer immunotherapy: targeting B-cells. While immunotherapy ...

Saved from precursor B-cell acute lymphoblastic leukemia, the Nobel Prize winning CAR T-cell therapy gave Bryn Ailinger a very merry Christmas ...

In a person living with HIV, proviruses—strands of HIV DNA—are typically integrated into the T cell genome and become a ...