Recent advances in optical physics have redefined the classical boundaries imposed by diffraction. Super-resolution imaging techniques, which once adhered strictly to the Rayleigh criterion, now ...

eDL-cSIM: An AI-driven super-resolution imaging method that captures high-quality live-cell dynamics in a single exposure, enhancing speed, resolution, and environmental robustness for advanced ...

Ricardo Nunes Bastos from Oxford Nanoimaging (ONI) discusses how lipid nanoparticles are redefining drug delivery and highlights new imaging tools that are unlocking the delivery vehicles’ full ...

Researchers from the University of Science and Technology of China (USTC) have unveiled a planar optical device that significantly enhances the capabilities of dark-field microscopy, achieving ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Scientists at the Center for Cell Dynamics, School of Biological and Behavioral Sciences, Queen Mary University of London, in collaboration with Carl Zeiss, have developed an innovative live-cell ...

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

Existing super-resolution techniques still face considerable challenges in complex deep tissue environments. For example, Stimulated Emission Depletion (STED) microscopy relies on a doughnut-shaped ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Researchers in Göttingen have developed a dedicated microfluidics system that improves reproducibility and accessibility in multiplexed super-resolution microscopy, allowing scientists to ...