A tumor “don’t‑eat‑me” shield also hides pro‑immune danger signals; new antibodies that unmask this hidden cue could make cancers more vulnerable to immune attack.

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

A hidden molecular chain reaction in the brain may push key cellular systems into overdrive in autism—and scientists just found a way to switch it off.

Researchers have uncovered a surprising molecular chain reaction in the brain that may play a role in some forms of autism.

Breast cancer is the second highest diagnosed cancer in women in the US and, as of 2020, the most commonly diagnosed cancer in women worldwide. 1 In 15–20 percent of these cases, the growth factor ...

Macrophages remain ready to fight infection thanks to signaling molecules left behind by previous infections. That is according to new research from scientists at the University of California, Los ...

Dental pulp regeneration remains a major clinical challenge. Researchers have discovered that SMAD7 directly forms a ...

In 2010, a large study in Denmark found that women who suffered an infection severe enough to require hospitalization while pregnant were much more likely to have a child with autism (even though the ...

Collagen plays dual roles in pancreatic cancer: as a physical fiber that obstructs macromolecular drug delivery, and as a bioactive signaling molecule that activates discoidin domain receptor 1 (DDR1) ...

Cornell researchers have uncovered a built-in molecular “gate” that controls the production of the molecule nitric oxide, a crucial signaling molecule throughout biology that in humans helps regulate ...