The San Francisco 49ers' fears about the injury to rookie defensive end Mykel Williams were confirmed Monday afternoon when a source told ESPN's Jeremy Fowler that Williams tore the anterior cruciate ligament in his right knee.

Late in the fourth quarter, first-round pick defensive end Mykel Williams went down with a right knee injury. Afterwards, coach Kyle Shanahan told reporters that they fear Williams injured his ACL. A torn ACL would sideline Williams for the remainder of the season.

Meanwhile, Christian McCaffrey recorded his longest run and longest reception of 2025 in the offensive line's best run-blocking game so far.

The San Francisco 49ers are in a tough spot when it comes to the trade deadline. The record says they are obvious buyers, but the roster continues to lose players, which makes you wonder how high the ceiling is.

The 49ers have been besieged by injuries for a second season in a row, and they desperately need more healthy bodies.

When the San Francisco 49ers and Los Angeles Rams meet this Sunday, offensive tackle Trent Williams will be suiting up for his 78th game with the red and gold. But according to an interview Williams gave the Athletic in a story published on the eve of the NFL trade deadline,

The Niners were fresh off a roster revamp, saying goodbye to nearly 20 players in the offseason, 15 of whom landed deals elsewhere worth up to a maximum of $341.5 million. In their place, the 49ers leaned into their youth, with an 11-man draft class and a free agent group that had no marquee players.

A lot is going on with the San Francisco 49ers. From key injuries to selling off shares of the team, the 49ers are never boring. Despite the many injuries, though, San Francisco is 5-2, with a chance to improve its record and stay atop the NFC West. But first, they'll have to...