Prolonged exposure to nicotine rewires specific brain circuits to dramatically increase the motivation to work for food, ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal-driving ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal—driving ...

Recent laboratory research reveals that a chemical compound known for inducing psychedelic effects reduces the motivation to consume cocaine in animal models. The findings suggest that targeting ...

A new therapy targeting reward circuits is "rewiring" the brain to restore joy in depression. See how Positive Affect ...

Motivation is less fragile than people think. More often, what causes it to fail is the result of years of gradual erosion ...