Triple-negative breast cancers (TNBC) are a particularly aggressive breast cancer subtype with poor prognosis and high relapse rates. Due to a lack of identified targeted therapies, chemotherapy ...

Bulk RNA sequencing has advanced transcriptomic analysis across diverse biological systems, but averaging gene expression across cell populations can obscure important cellular differences.

Tumor samples were obtained from retinoblastoma patients undergoing primary enucleation (PE). No patients received prior systemic or intraocular therapy. Enucleation status and clinical details are ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

Understand the stages of a standard RNA-seq bioinformatics workflow, including the role of QC, alignment, gene expression quantification, and specialized application analyses Identify key QC metrics ...

Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how genetic variants disrupt gene function and improve the diagnosis of rare ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Plasmidsaurus has launched a new RNA-Seq service for Illumina short read applications, bringing the same approach they use for plasmid sequencing to gene expression analysis. Attendees at this week’s ...

Association between molecular changes and perioperative immunotherapy in patients with advanced clear cell renal cell carcinoma undergoing cytoreductive nephrectomy. This is an ASCO Meeting Abstract ...

Diabetic foot ulcer (DFU) is one of the most serious complications of diabetes and a major cause of lower-limb amputation.

Single-cell sequencing is useful for a number of applications. For example, it can reveal cellular heterogeneity inside complex tissues, such as tumors. It can also provide information about how ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...