A patient developed monomorphic B-cell posttransplant lymphoproliferative disorder (PTLD) of immunoblastic type (Epstein-Barr virus [EBV]+) in her renal transplant 2 months after transplantation. She ...

Central nervous system (CNS) PTLD generally carries a dismal prognosis. It is seen in both children and adults and about half of cases occur in isolation, with the rest occurring in the setting of ...

The occurrence of post-transplant lymphoproliferative disorder (PTLD) in relation to immunosuppressive treatment was determined in 257 patients treated with non-T-cell-depleted allogeneic stem cell ...

Post-transplant lymphoproliferative disease (PTLD) is an aggressive and potentially fatal hematologic malignancy that can occur following transplantation due to immunosuppression. Nearly all PTLD ...

Recipients of solid-organ transplants receive immunosuppressive therapy to prevent allograft rejection. Immunosuppressive therapy can be divided into induction therapy, administered in the ...

Transplants can trigger EBV reactivation, leading to EBV-positive PTLD, with poor survival if rituximab fails. Tabelecleucel (tab-cel) shows promise in treating refractory EBV+ PTLD, with significant ...

Please provide your email address to receive an email when new articles are posted on . More than half of patients treated with tabelecleucel for Epstein-Barr virus-driven post-transplant ...

Fred Hutchinson Cancer Center is home to some of the world’s most advanced cancer treatments, including CAR T-cell therapy for post-transplant lymphoproliferative disorder (PTLD). Physicians in the ...

First allogeneic T-Cell therapy BLA offers hope to EBV+ PTLD patients who have limited treatment options and lifespan measured in only a few weeks to months following failure of initial treatment EBV+ ...

Duration of response in three phase III studies of denileukin diftitox in cutaneous T-cell lymphoma (CTCL). Background: PTLD represent a serious complication of both solid organ and bone marrow ...

Activity of fludarabine in previously treated Waldenström's macroglobulinemia: a report of 71 cases. Groupe Coopératif Macroglobulinémie. There were seven kidney, three heart, and one liver transplant ...

PTLD develops in approximately 1 in 5 recipients of EBV-positive donor kidneys, a much higher rate than previously thought. Recipients of kidney transplants infected with Epstein-Barr virus (EBV) have ...