Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...

snoRNAs were thought simply to guide chemical modifications to rRNAs, but a new technique has revealed a suite of potential functions in protein secretion. A recent research effort from the University ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

Plant cell-based bioproduction systems are known for producing proteins with proper folding and post-translational modifications that have been used in a handful of approved therapeutics. Widespread ...

Machine-learning platform enables signal peptide-informed discovery of small molecules that selectively inhibit protein secretion allowing for the degradation of disease-related proteins at the point ...

Protein is the essential macronutrient that helps build your bones and muscles. It also helps repair your tissue damage and ...

The human brain, like the brain of other mammals, is known to start developing before birth, via a coordinated sequence of molecular and cellular processes. Neuroscience studies have found that the ...