Suzanne Jansen, MSc, PharmD, ICON, says early-phase clinical success depends on flexible, simple formulations that support ...

In the evolving landscape of pharmaceutical development, modified release (MR) tablets have emerged as a cornerstone technology for improving therapeutic outcomes and patient compliance. Unlike ...

Fizzy drug formulations may pose CV risk Taking effervescent medication on a regular basis may increase patients' risk for cardiovascular events due to excess sodium. Effervescent, dispersible and ...

To optimize the final formulation for a drug, it must meet many criteria beyond producing a safe and effective product. For example, it must be stable and amenable to various manufacturing steps, such ...

Highly potent but poorly water-soluble drug (PWSD) candidates are common outcomes of contemporary drug discovery programmes. These lipophilic compounds often exhibit poor systemic exposure following ...

Researchers at the University of Toronto say they have successfully tested the use of machine learning models to guide the design of long-acting injectable drug formulations. The potential for machine ...

Scientists have successfully tested the use of machine learning models to guide the design of long-acting injectable drug formulations. The potential for machine learning algorithms to accelerate drug ...

Early on, the drug substance (DS) manufacturer will provide a wealth of preliminary characterization data. And if the drug is active in early nonclinical and preclinical testing, a larger quantity of ...

In this interview, NewsMedical speaks with Joanna Lipner, Co-Founder of PIKRALIDA, and Hanna Kierońska, Head of Drug Technology, about the company’s approach to reducing polypharmacy, drug formulation ...

The assistance of an analyst is often sought after for determining an analyte in scenarios where the elimination or accurate reproduction of a matrix in a blank sample is not possible. Such scenarios ...

The media have been replete with reports of ways in which the pharmaceutical industry has been able to increase revenue from medications that have been available for decades. 1 We report a new ...