Formalin-fixed paraffin-embedded (FFPE) tissues have long served as invaluable resources in biomedical research, particularly in clinical and translational studies. Despite the inherent challenges ...

A prospective, non-interventional study among patients diagnosed with locally advanced or metastatic non–small-cell lung cancer to assess the adherence to oral antineoplastic therapy from data ...

For decades, formalin-fixing paraffin-embedding has been the preferred method for preserving biological samples for diagnostic research. Formalin is relatively inexpensive and can be used to preserve ...

Precise, tailored cancer diagnosis and treatment, known as precision oncology, is gaining steam. But most methods able to look deeply at the molecular characteristics of a patient’s tumor rely on ...

Next-generation sequencing (NGS) has transformed genomic research and clinical diagnostics by enabling rapid, high-throughput analysis of genetic material. The application of NGS to formalin-fixed ...

Tissue microarrays combines tens to hundreds of paraffin-embedded tissue cores into a single paraffin block. It is a practical and highly effective technique for high-throughput analyses of various ...

Nimotuzumab plus chemotherapy versus chemotherapy alone in advanced non-small cell lung cancer: A phase II, open-label, multicenter, randomized study. This is an ASCO Meeting Abstract from the 2013 ...

To detect estrogen and its metabolites in the ovarian-type stroma of pancreatic mucinous cystic neoplasm (MCN) tumors, researchers applied a novel liquid chromatography–tandem mass spectrometry (LC-MS ...

The two main fixation formats used by researchers are formalin fixation followed by paraffin embedding (FFPE) or snap-frozen in liquid nitrogen (referred to as Fresh Frozen or FF). There is less of a ...

Article reviewed by Govind Kaigala, PhD at the University of British Columbia. Stay up to date on the latest science with Brush Up Summaries. In situ hybridization (ISH) is a molecular technique that ...

Researchers have developed a method for mapping the orientation and organization of tissue fibers, furthering our ...