A growing body of researchers is utilizing optical imaging to monitor activity in the brain. One type of optical imaging, two-photon calcium imaging, has been widely adopted for its ability to record ...

I still vividly remember the first time we observed neurons responding not to audible sound, but to concentrated, precisely calibrated ultrasonic pulses. On the screen in front of us, calcium signals ...

(1) A nerve impulse arrives. (2) This causes calcium ion channels to open, resulting in an influx of calcium ions in the terminal. (3) This causes synaptic vesicles to fuse with the terminal membrane, ...

A project at the Kavli Institute for Systems Neuroscience (KISN) based at the Norwegian University of Science and Technology has announced new results in large-scale 2-photon calcium imaging in freely ...

A large barrier in neuroscience is the ability for researchers to conduct studies on a live, functioning brain without surgery or implanting probes. Today researchers at the Massachusetts Institute of ...

Clusters of proteins found on neurons are calcium-signaling “hotspots” that link electrical signals to gene expression, allowing neurons to produce crucial proteins. The discovery may potentially lead ...

Nerve cells regulate and routinely refresh the collection of calcium channels that enable them to send messages across circuit connections. The nervous system works because neurons communicate across ...

In cell signaling, calcium is king. The flux of calcium ions across cell membranes regulates cellular activities from muscle contraction to neuron firing to immune cell function. A talk I saw here at ...

Decades before Alzheimer’s disease symptoms appear, neurons become hyperactive, and the reason could be that astrocytes fail to keep them in check. In a bioRxiv preprint uploaded on April 26, ...

Neuroscientists examining a brain cell typically have to choose between studying its internal molecular activity or detailing its connections and electrical activation in the brain. But in his lab at ...