A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its ...

A pair of USC Stem Cell mouse studies detail how progenitor cells self-renew, differentiate, and aggregate into early kidney structures, offering insights for the creation of stem cell-based ...

“You’re on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can’t handle it. You’re harming them.” ...

Synthetic organizers provide a way to control formation of kidney organoids as more reliable models for studying disease and ...

Each human kidney is made up of about a million filtering units called nephrons. I aim to reveal the mechanisms behind a key stage of nephron development during which a structure known as an S-shaped ...

The purpose of this communication is to present certain data pertinent to this syndrome and to suggest that treatment based on the pathological physiology of this type of renal failure offers ...

Glomeruli are at the heart of renal function, and yet are only part of an intact nephron. They are of irreplaceable value in maintaining homeostasis. The intact nephron theory: Each nephron is a ...