For a long time, evolutionary biologists have thought that the genetic mutations that drive the evolution of genes and proteins are largely neutral: they're neither good nor bad, but just ordinary ...

It's time for researchers to reconsider the current paradigm of cancer as a genetic disease, argues Sui Huang from the Institute for Systems Biology, U.S., and colleagues in an essay published in the ...

Mutation dynamics and fitness effects lie at the heart of evolutionary change. Every generation, genomes accrue spontaneous alterations ranging from single-nucleotide substitutions to larger ...

The neutral theory of molecular evolution, positing that most amino acid substitutions in protein evolution are neutral, is supported by vast comparative genomic data. However, here we report that the ...

A University of Michigan-led study based on a review of genetic and health information from more than 276,000 people finds strong support for a decades-old evolutionary theory that sought to explain ...

It's time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the Institute for Systems Biology, USA, and colleagues in a new essay published March ...

An international team of scientists headed by researchers at the University of Edinburgh, has created a complete map showing how hundreds of possible mutations in a key cancer gene, CTNNB1, influence ...

Researchers at University of California San Diego School of Medicine have published results that shed new light on an old question: what causes aging at the molecular level? Their findings, published ...

It's time for researchers to reconsider the current paradigm of cancer as a genetic disease, argue authors of a new essay. It's time for researchers to reconsider the current paradigm of cancer as a ...

Two major theories of aging both involve DNA, but in very different ways. Researchers have revealed that these theories may not be so different after all. Researchers at University of California San ...

3D structure of a melanoma cell derived by ion abrasion scanning electron microscopy. It’s time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from ...