All proteins are made of basic secondary structure units, either α-helix or β-sheets, determined by hydrogen bonding between the amino acids within a peptide chain. On a larger scale, structures are ...

An iterative machine learning approach has identified elusive 800 million-year-old amino acid patterns that are responsible for facilitating protein interactions. Leucine-aspartic acid (LD) motifs are ...

The ability to accurately integrate proteins into signaling pathways is critical for functional annotation of genome sequences, as well as for understanding the relevance of known and newly discovered ...