Anaemia is a frequent and clinically relevant complication of systemic lupus erythematosus (SLE), particularly in patients ...
Mutations in FANCX appear to cause a lethal form of Fanconi anemia, a finding that sheds light on unexplained pregnancy loss and offers new avenues for genetic screening. Fanconi anemia is an ...
Fanconi anaemia (FA) is a genetically heterogeneous disorder characterised by congenital abnormalities, progressive bone marrow failure and a high risk of malignancy. At its core lies a specialised ...
Efficacy and safety data from Ph1b, dose optimization trial of two doses of TH1902 (sudocetaxel zendusortide), a novel SORT1-targeting peptide drug conjugate (PDC), administered weekly vs q3weekly in ...
Fanconi anemia is an aggressive, life-threatening disorder. Most individuals living with this rare genetic condition, characterized by bone marrow failure and cancer predisposition, survive into ...
Posttransplant anaemia is a common and multifactorial complication affecting kidney transplant recipients throughout the early and late post-transplant periods. Early anaemia, occurring within the ...
The ‘heart’ of the Fanconi anemia core complex, composed of FANCB-FANCL-FAAP100 (now FANCX) proteins, allows the rest of the core complex to assemble, and is necessary for downstream DNA repair.
Fanconi anemia is an aggressive, life-threatening disorder. Most individuals living with this rare genetic condition, characterized by bone marrow failure and cancer predisposition, survive into ...
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