Parents can be reassured that their children are at very low risk of suffering a malignant hyperthermia reaction to an anaesthetic, says specialist anaesthetist Dr Terasa Bulger. “And should they ...

Early in the course of the development of these agents, haloperidol was found to cause not only hypokinetic and hyperkinetic motor disorders but also a potentially fatal syndrome of muscle rigidity ...

The discovery and subsequent introduction of dantrolene in 1979 was a major breakthrough in the treatment of malignant hyperthermia (MH) that is responsible for saving hundreds, if not thousands, of ...

Malignant hyperthermia is an autosomal dominant pharmacogenetic disorder of skeletal muscle characterised by a hypermetabolic response to certain volatile anaesthetics and depolarising muscle ...

Hot summer temperatures may have you reaching for a fan and an iced drink in your quest to keep cool. But now, researchers from Japan have found that some mutant proteins are even less tolerant of the ...

In their presentation of a case of rhabdomyolysis possibly associated with mRNA SARS-CoV-2 vaccination, Salter and colleagues1 are to be commended for elucidating the relevant differential diagnosis, ...

Congratulations to Dr. Stacey Watt of Health/Malignant Hyperthermia Associaton of the U.S., one of this year's ...

A team of researchers has found that mutations in the calcium channel protein RyR1 that confer susceptibility to malignant hyperthermia make the protein hypersensitive to heat, which triggers ...

Malignant hyperthermia is an uncommon disorder that presents in an ambulatory surgery center utilizing general anesthesia. Preparation for management of this condition needs to be a significant part ...

Correspondence to: Professor P M Hopkins Malignant Hyperthermia Investigation Unit, Academic Unit of Anaesthesia, St James’s University Hospital, Leeds LS9 7TF, UK;p.m.hopkins{at}leeds.ac.uk If you ...

Malignant hyperthermia crises come on suddenly, and healthcare providers have no real way to predict which patients may experience this reaction while under anesthesia unless they have found a ...