The clearance of misfolded and unfolded proteins is mainly performed by the ubiquitin–proteasome system (UPS) 1,2, whereas macroautophagy and lysosomal degradation, the other major routes of ...

This is a guitar specifically designed to make eardrums bleed. It's not for the faint-hearted, but we'd expect nothing less. The 'Seven' inlay and tuning might put some people off. MusicRadar's got ...

Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) ...

In order for the body to function, cells need a constant supply of energy. During phases of starvation, when no nutrients are taken up from food, the cellular metabolism must adapt to ensure a ...

As a guitarist in one of metal's most brutal acts, Slipknot's Mick Thomson demands a lot from his gear. His signature line of guitars from Ibanez helps him deliver the punishing riffs that help form ...