Bethesda, MD – In response to the growing number of lipids expected to be discovered through lipidomics and in anticipation of the massive amounts of data that will be generated by the lipid community ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. A team led by ...

Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big impact on how well our cells absorb them, paving the way to more efficient ...

An AI-identified lipid called P1 delivered mRNA 14.8 times more efficiently than the clinically approved lipid ALC-0315. Lipid P1's unique three-dimensional conformation allows it to bind ...

Chemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic diseases such as obesity and diabetes. In addition, it plays a critical role ...

To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...

The bottom of the ocean is not hospitable: there is no light, the temperature is freezing cold, and the pressure of all the water above will literally crush you. The animals that live at this depth ...