Human organoids are 3D cell cultures derived from adult stem cells and maintain the variable distribution of epithelial cells seen in primary tissue. They can recapitulate the mechanisms of epithelial ...

Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...

Chinese Medical Journals Publishing House Co., Ltd. The small intestine is not only essential for digestion and nutrient absorption but also for immune regulation and maintaining a balanced microbial ...

Gut support cells communicate with surprising precision – like brain neurons – using tiny extensions to send instructions to the stem cells responsible for maintaining and healing the intestine. The ...

Researchers discover a calcium-mediated effect that helps preserve the integrity of the sheets of cells lining our bodies and organs. Fukuoka, Japan—A research team from Kyushu University in Japan has ...

Memorial Sloan Kettering Cancer Center researchers have identified a metabolic switch that determines whether intestinal stem cells become absorptive or secretory cells. Manipulating the enzyme OGDH ...