Drug hypersensitivity reactions are drug reactions which are unpredictable. They result from an interaction between a drug substance and the immune system of a hypersensitive person. Hypersensitivity ...

Hypersensitivity reactions induced by proton pump inhibitors (PPIs) represent a growing concern given the extensive use of these agents for managing acid-related disorders. Although PPIs are generally ...

Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to ...

It is the strength of these associations, and potential involvement in the immune reaction, that has seen these alleles suggested as candidates for pharmacogenetic testing either as predictive or ...

Corticosteroid hypersensitivity reactions are an uncommon yet clinically significant phenomenon that can pose challenges in the management of patients requiring steroid therapy. These reactions may be ...

Cetuximab, a chimeric mouse–human IgG1 monoclonal antibody against the epidermal growth factor receptor, is approved for use in colorectal cancer and squamous-cell carcinoma of the head and neck. A ...

Does radiation therapy contribute to breast cancer–related lymphedema after axillary node dissection? A simplified lymphatic microsurgical preventative healing approach (S-LYMPHA). This is an ASCO ...

Sociodemographic Inequities in Telemedicine Use Among US Patients Initiating Treatment in Community Cancer Centers During the Ongoing COVID-19 Pandemic, 2020-2022 Based on our observations, it is ...

A 35-year-old man of Chinese ethnicity presented to the emergency department with fever, rash, mouth pain and visual impairment after two weeks of therapy with allopurinol. On examination, the patient ...

1 Department of Microbiology & Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia. An increasing number of HLA associations have been observed with drug-hypersensitivity ...