The main component of Alzheimer’s plaques—fibrillar aggregates of amyloid-β(1-42) (Aβ42)—pose a sticky problem for structural biologists. In the past few years, groups have used various biophysical ...

This is a preview. Log in through your library . Abstract Amyloid-β (Aβ) fibrils exhibit self-propagating, molecular-level polymorphisms that may contribute to variations in clinical and pathological ...

Bucking conventional, i.e., left-leaning, wisdom for amyloid fibrils, Aβ fibrils extracted from the brains of three people with Alzheimer’s disease all twisted to the right. This is apparent in the ...

In the knee joint, articular cartilage and meniscus work synergistically to enable daily activities such as walking, running, and jumping. Although injuries of these two tissues are common, the ...

Jülich / Düsseldorf / Hamburg / Maastricht, 7 September 2017 - A team of researchers from Germany and the Netherlands have determined the structure of an amyloid fibril with previously unachieved ...

Study may be a step toward shelf-stable versions of the hormone, which is used to control diabetes. Patients with type 1 diabetes have to regularly inject themselves with insulin, a hormone that helps ...

This is a preview. Log in through your library . Abstract The distribution, supramolecular form, and arrangement of collagen types I and V in the chicken embryo corneal stroma were studied using ...

Researchers at MIT have been conducting research that could help people who have type 1 diabetes. People with that medical condition have to inject themselves with insulin to allow their body to ...

Parkinson's disease was first described by a British doctor more than 200 years' ago. The exact causes of this neurodegenerative disease are still unknown. Scientists now questioned the previous ...

Patients with type 1 diabetes have to regularly inject themselves with insulin, a hormone that helps their cells absorb glucose from the bloodstream. Another hormone called glucagon, which has the ...