Researchers have created what could be a key building block for assembling a synthetic kidney. They describe how they generate rudimentary kidney structures, known as organoids, that resemble the ...

Being able to grow working kidney tissue from human pluripotent stem cells (hPSCs) is essential to kidney regenerative medicine and could help accelerate medical treatments for kidney disease and ...

Do you recognize the shape of this yellow tree-like structure? If you guessed a kidney, you are correct! It is the collecting duct system, which funnels urine from the kidney to the bladder. And what ...

A phase I/II study of sitravatinib (MGCD-516) plus nivolumab in patients (pts) with metastatic clear-cell renal cell carcinoma (ccRCC) that progressed on prior VEGF-targeted therapy. Background: ...

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world. Being able to grow working kidney tissue in a laboratory could help ...

A research project has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. Although cysts derived from renal tubules have ...

Tuberous sclerosis complex (TSC) afflicts as many as two million people around the world, affecting multiple organs, including lungs, brain, skin, and kidneys. In about 80 percent of cases, it causes ...

Tuberous sclerosis complex (TSC) afflicts as many as two million people around the world, affecting multiple organs, including lungs, brain, skin and kidneys. In about 80 percent of cases, it causes ...