Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

Drugs originally designed to treat diabetes and obesity are reshaping medicine in unforeseen ways. Their impact on public health is really unprecedented in modern times, perhaps only upstaged by ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...

I don’t drink anymore. I don’t smoke anymore.” He might have shrugged it off, but reports accumulated in his clinic and ...

Within the brain, chemical neurotransmitters like dopamine and norepinephrine regulate mood, emotions and many physiological and behavioral processes. Their imbalance can contribute to anxiety, ...

GLP-1 medications may quiet the brain signals behind addiction, reducing substance use disorders and overdose risk across ...

Your endless scroll may be costing you more than just your time. New research shows it’s changing the way you think and make decisions. These days, almost everything is available in the form of quick, ...

(THE CONVERSATION) Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse ...