Nature

Successful nonmyeloablative bone marrow transplantation in a corticosteroid-resistant infant with Diamond–Blackfan anemia

A conditioning regimen based on fludarabine and low-dose TBI (2 Gy) permits engraftment and full donor chimerism in both malignant and nonmalignant diseases, and can potentially avoid complications ...
News Medical

Bone marrow chip provides new strategy for understanding Shwachman-Diamond syndrome

A new research tool that mimics the behavior of diseased bone marrow provides a new strategy for understanding the bone marrow disease, Shwachman-Diamond syndrome (SDS), and hopefully, developing new ...
Nature

First experience of hematopoietic stem cell transplantation treatment of Shwachman–Diamond syndrome using unaffected HLA–matched sibling donor produced through ...

The only proven cure for Shwachman–Diamond syndrome (SDS) bone marrow failure is allogeneic hematopoietic stem cell transplantation (HSCT). However HSCT with donors other than HLA-identical siblings ...