They will head out on the road to face off against the Arizona Cardinals at 4:05 p.m. ET at State Farm Stadium. The 49ers will be looking to extend their current five-game winning streak. Last Sunday,

Arizona Cardinals running back Trey Benson suffered a knee injury in Week 4 of the 2025 NFL season. Here's what we know about his potential return:

Mac Jones will be under center for the seventh time for the 49ers when they play at the Giants, as Brock Purdy moves closer to a return. The former New England first-round pick and starter has kept San Francisco in the playoff picture with victories in four of his six starts.

When you watch Brock Purdy at practice, he seems healthy enough to play. He can run. He can throw. He looks like Brock Purdy. But he almost certa

Arizona Cardinals quarterback Kyler Murray won't be under center for Monday night's game against the Dallas Cowboys.